Her destination: New Jersey.
She's on a mission to help in one of the hardest hit areas devastated by Sandy, the hurricane turned superstorm that lashed the coast earlier this week. The storm was a monster, disrupting millions of lives and causing billions of dollars-worth of damage.
Wolfe is a registered nurse with valuable skills to offer in emergency situations -- she is an American Red Cross volunteer.
Wolfe grew up in Worthington, the daughter of Jack and Jeanette Wolfe, and graduated from Worthington-Jefferson High School in 1965. She went on to pursue a nursing degree, attending Indiana State University and the St. Anthony Hospital School of Nursing, graduating with the Class of 1971. After a long career in the nursing field, Wolfe has recently retired.
When she arrives in the heart of the Sandy disaster, at age 65, she'll be carrying 40 years of full-time nursing experience.
Late Thursday, her status with the Red Cross was ready, willing and able when she received notice that she was being deployed.
She expects to be serving as a nurse in one of the shelters established to house people who cannot yet return to their homes, or whose homes have been destroyed.
She's done this before, in the aftermath of Hurricane Katrina, but this time is a little different.
"I was deployed as a shelter nurse during Katrina, but it was later in the event. This time, it's early," said Wolfe.
By going in to help in the first days after the storm, emotions and tensions are likely to be running high.
Wolfe arrived at the airport early and called home while she was waiting to board her flight. There had been a few glitches in her morning -- the ATM did not want to work.
"I have some preflight jitters," said Wolfe. "But I'm ready to get to work."
Her flight to Charlotte, North Carolina was scheduled to take off at 9 a.m. In Charlotte, she'll catch another flight bound for Newark, New Jersey.
Her deployment is expected to last two weeks.
As she waited in the airport, Wolfe admitted she was a bit nervous but the messages of support she received from a few friends had helped to encourage her. Wolfe doesn't post often on Facebook, but Thursday she posted, "Here I go, out with the Red Cross to the East Coast. Pray for me." It was quickly noticed and several friends reacted. One said, "I'm not surprised that you're going.......you're The Best." Others wished her luck, blessings, safe travels and Godspeed.
It's not known whether she will have access to a computer or to the Internet, but Wolfe plans to keep in touch with the Greene County Daily World as much as possible. If news is received from Wolfe, an update will be posted online.